PharmaGABA® is the registered trademark for GABA of Pharma Foods International Co., Ltd.
Gamma-aminobutyric acid (GABA) is a major neurotransmitter that is abundantly and widely distributed throughout the central nervous system (CNS).
Low levels or decreased GABA function in the brain is associated with several psychiatric and neurological disorders, but most primarily anxiety, depression, insomnia, and epilepsy.
Many popular anti-anxiety drugs interact primarily with GABA receptors. These drugs include the benzodiazepine drugs like alprazolam (Alprazolam, Xanax) and diazepam (Valium); as well as drugs like flurazepam (Dalmane); quazepam (Doral); temazepam (Restoril); triazolam (Halcion); zolpidem tartrate (Ambien); and baclofen (Kemstro, Lioresal). All of these drugs mimic the effects of GABA in a distorted manner and are associated with significant risks and side effects.
In clinical studies, PharmaGABA has been shown to produce relaxation as evidenced by changes in brain wave patterns, diameter of the pupil, and heart rate as well.
Once ingested, it appears that the PharmaGABA is absorbed easily and binds to GABA receptors in the peripheral nervous system leading to activation of the parasympathetic nervous system. This arm of the autonomic nervous system is responsible for producing what is referred to as the “relaxation response,” a physiological response that is in direct contrast to the stress or “fight or flight” response. This activation of the parasympathetic nervous system is measurable within 5 to 30 minutes after ingestion.
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